RFA Opportunities

The Discovery Research program supports an innovative and collaborative group of researchers working together to improve our understanding of the biological mechanisms that underlie bipolar disorder. For this funding cycle, we especially encourage applications that address the cellular and molecular mechanisms of mood-state switching; biological mechanisms by which manic or depressive episodes are induced by external risk factors; or using experimental pharmacology to test causality of a molecular or circuit-level mechanism underlying mood-state switching.

BD² seeks applications from qualified organizations or teams to develop and manage a comprehensive mobile application system for data collection, monitoring, and analysis for the Integrated Network. The BD² Integrated Network is part of a multidisciplinary initiative to increase the scientific understanding and, ultimately, to improve care and interventions for bipolar disorder.

The BD² Integrated Network, in partnership with people living with bipolar disorder and their care teams, engages a network of collaborating investigators and clinicians to build an unprecedented data ecosystem for bipolar disorder, implement and inform data-driven improvements in care, and generate novel insights for interventional approaches.

The Discovery Research program aims to delineate the etiology and biological mechanisms of bipolar disorder, allowing the development of effective interventions. We fund multidisciplinary teams of scientists and clinicians who generate new hypotheses and drive innovation in the exploration of causal mechanisms of bipolar disorder with an eye toward novel treatments.

The Discovery Research program supports an innovative and collaborative group of researchers working together to improve our understanding of the biological mechanisms that underlie bipolar disorder. We seek multidisciplinary teams of scientists to develop targeted and groundbreaking research applications that will examine the genetic, molecular, cellular, circuit, and/or behavioral mechanisms of bipolar disorder.

As part of the BD² Integrated Network, the CCC provides expert guidance and logistical support including key diagnostics and clinical assessments, Institutional Review Board activities, a rigorous study monitoring plan, and coordination of clinical care activities.

As part of the BD² Integrated Network, the DCC provides technical and logistical support for iterative cycles of data aggregation, analyses, and implementation.

In partnership with people living with bipolar disorder, clinicians, and researchers, the BD² Integrated Network brings together a community committed to dramatically improving systems of care and accelerating research. Integrated Network sites make up a learning health network (LHN) with the goal of rapid integration of data analytics from research to inform clinical care.